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Bread Consumption and Cancer Risk: Systematic Review and Meta-Analysis of Prospective Cohort Studies

A study published in Current Developments in Nutrition and selected as an Editors’ Choice in ASN’s newsletter reveals reassuring insights about bread consumption.

Conducted by GFF’s Scientific Advisory Board members, Dr. Glenn A. Gaesser and Dr. Siddhartha S. Angadi, a comprehensive meta-analysis of 24 studies encompassing nearly 1.9 million participants, primarily from Europe, concluded that bread intake does not increase cancer risk.

Key findings:

  • Bread consumption is not associated with increased site-specific cancer risk, whereas high whole-grain bread consumption is associated with lower total cancer mortality.
  • Whole-grain bread was found to be associated with a lower site-specific cancer risk mainly due to reduced colorectal cancer risk.
  • The study concluded that it is unlikely that heat toxins produced in bread in the amounts customarily eaten have any appreciable impact on cancer incidence or mortality.
  • A limitation of the analysis is the insufficient number of studies on white bread consumption, making it challenging to draw definitive conclusions about its association with cancer risk.

These findings underscore the importance of grains in a healthy diet while addressing key questions about bread consumption and cancer risk.

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Bread Cancer Refined grain Tags: bread, cancer, carbohydrates, refined grain

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